| Primary Identifier | MGI:6790669 | Allele Type | Endonuclease-mediated |
| Gene | Acss2 | Strain of Origin | C57BL/6N |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology generated a single nucleotide deletion in the ABC domain and introduced a stop codon following addition of one nonnative amino acid residue (LPKTRSGKIMRR... to LPKTRSGKIS*). Immunohistochemistry shows that protein is present at minimal or undetectable levels in the kidney and liver, respectively and mRNA levels are reduced in kidney and liver. |
