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Allele : Pparg<tm1.1Sakl> peroxisome proliferator activated receptor gamma; targeted mutation 1.1, Steven A Kliewer

Primary Identifier  MGI:6791383 Allele Type  Targeted
Attribute String  Not Specified Gene  Pparg
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6J)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A mutation was engineered to change isoform 2 lysine codon 107 in exon 3 (AAA) to arginine (AGA)(p.K107R) and an FRT site flanked neomycin resistance gene cassette was inserted into intron 3. The neo cassette was removed through subsequent flp-mediated recombination. The mutation prevents SUMOylation of the residue in the encoded peptide.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • PPARgamma-K107R,
  • PPARgamma-K107R
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories