| Primary Identifier | MGI:6780118 | Allele Type | Targeted |
| Attribute String | Recombinase | Gene | Nkx2-2 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | A DNA construct with COOH-terminal Cre (cCre)-T2A and Frt-flanked hygro selection cassette were inserted using recombineering into an Nkx2-2 basal exchange vector such that Ccre was fused in-frame with the ATG start codon. The modified Nkx2.2 locus and a hygromycin selection cassette were flanked by Lox66 and Lox2272 elements. This vector was co-injected with a cre-expression vector into ES cells containing an Nkx2-2 |
