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Allele : Apoe<tm2.1(APOE_i3)Hol> apolipoprotein E; targeted mutation 2.1, David M Holtzman
Primary Identifier  MGI:6780676 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence, Null/knockout Gene  Apoe
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct replaced the coding sequence with a loxP site, FRT-flanked neomycin resistance cassette, the human coding sequence for isoform 3 (E3F) with signal peptide, an F3 flanked puromycin resistance cassette, loxP site, and human GH polyadenylation sequence. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Apoe<E3F>,
  • Apoe<E3F>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

11 Publication categories





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