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Allele : Mlkl<em2Mpa> mixed lineage kinase domain-like; endonuclease-mediated mutation 2, Manolis Pasparakis

Primary Identifier  MGI:6758929 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Mlkl
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing technology was used to generate a mutation in the Mlkl gene by microinjected with Mlkl short guiding (sg)RNA and Cas9 mRN into the pronucleus of fertilized oocytes obtained from breedings of K14-Cre; Ripk1fl/wt males with Ripk1fl/fl females.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Mlkl-,
  • Mlkl-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele