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Allele : Cachd1<em1Kjn> cache domain containing 1; endonuclease-mediated mutation 1, Kenneth R Johnson

Primary Identifier	MGI:6827308	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Cachd1
Inheritance Mode	Recessive	Strain of Origin	C57BL/6J
Is Recombinase	false	Is Wild Type	false

molecularNote

This 98 bp out-of-frame deletion and 1 bp G to A transition 4 bases later all within the protein coding sequence of exon1 was generated using CRISPR/cas9 mediated excision

mutations:
Intragenic deletion

earliestPublication:
Tian C, et al. (2021) CACHD1-deficient mice exhibit hearing and balance deficits associated with a disruption of calcium homeostasis in the inner ear. Hear Res 409:108327

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

3 Publication categories

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