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Allele : Foxp3<tm12.1(Hbegf/EGFP)Ayr> forkhead box P3; targeted mutation 12.1, Alexander Y Rudensky
Primary Identifier  MGI:6758784 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence Gene  Foxp3
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site; encephalomyocarditis virus IRES; diptheria toxin receptor (DTR) enhanced green fluorescent protein (eGFP) fusion protein; a triple SV40 polyA (STOP); a second loxP site; encephalomyocarditis virus IRES; Thy1.1; followed by a frt site-flanked PGK-Neomycin resistance gene (NEO)-BGHpA cassette (loxP-IRES-DTReGFP-STOP-loxP-IRES-Thy1.1-frt-NEO-BGHpA-frt) was inserted into the Foxp3 3' UTR via homologous recombination in ES cells. The mice were bred to FLPeR mice to excise the NEO cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Foxp3<fl-DTR>,
  • Foxp3<tm12.1(DTR/EGFP)Ayr>,
  • Foxp3<fl-DTR>,
  • Foxp3<tm12.1(DTR/EGFP)Ayr>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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