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Allele : Ptpn11<m1Btlr> protein tyrosine phosphatase, non-receptor type 11; mutation 1, Bruce Beutler

Primary Identifier	MGI:6760643	Allele Type	Chemically induced (ENU)
Attribute String	Not Specified	Gene	Ptpn11
Inheritance Mode	Recessive	Strain of Origin	C57BL/6J
Is Recombinase	false	Is Wild Type	false
Project Collection	Beutler Mutagenetix

molecularNote

ENU mutagenesis induced a T-to-A point mutation that results in the amino acid substitution of histidine with leucine at position 419 (p.H419L).

mutations:
Single point mutation

synonyms:
Ptpn11<H419L>,
Ptpn11<H419L>

earliestPublication:
Rios JJ, et al. (2021) Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice. J Bone Miner Res 36(8):1548-1565

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

3 Publication categories

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