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Allele : Ttc17<em1(IMPC)J> tetratricopeptide repeat domain 17; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6759775 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ttc17
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TGATGTCTCTGATTAAGAGA and AGTCAAGTATAATCAAAGAC, which resulted in a 263 bp deletion beginning at Chromosome 2 position 94,206,259 bp and ending after 94,206,521 bp (GRCm39/mm39). This mutation deletes ENSMUSE00001094860 (exon 6) and 153 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 221 and early truncation 2 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories