| Primary Identifier | MGI:6864155 | Allele Type | Targeted |
| Attribute String | Conditional ready | Gene | Kcnj2 |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Using homologous recombination in the ES cells, R67Q mutation found in humans with exertion-induced polymorphic ventricular tachycardia (PMVT), bidirectional ventricular tachycardia (BiVT) and syncope was introduced into the Kcnj2 gene. The target vector contained R67Q-KCNJ2 with a neo cassette inserted into the primary sequence, flanked with loxP sites. |
