| Primary Identifier | MGI:6860661 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Bcl2l11 |
| Strain of Origin | C57BL/6NJ | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Using CRISPR/Cas9 technology, a 27,282-bp central segment of the human BCL2L11 gene flanked by 12,773- and 26,632-bp homology arms (consisting of the proximal and distal regions of the mouse Bcl2l11 gene), respectively including a conditionally removable loxP-flaked-segment (2.9-kbp) of intron 2, a cryptic human exon immediately 3â² of this, and a native human exon some 20 kbp downstream replaced the mouse Bcl2l11 locus. |
