| Primary Identifier | MGI:6794059 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Fbxo3 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGTTTGTTTCCTCTCAACGT and TTACATTATGGACTGCTATA, which resulted in a 490 bp deletion beginning at Chromosome 2 position 103,873,026 bp and ending after 103,873,515 bp (GRCm39/mm39). This mutation deletes ENSMUSE00001252280 (exon 4) and 375 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 119 and early truncation 17 amino acids later. |
