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Allele : Cttnbp2<em3Yph> cortactin binding protein 2; endonuclease-mediated mutation 3, Yi-Ping Hsueh

Primary Identifier  MGI:6761318 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Cttnbp2
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a G to A change resulting in a methionine to isoleucine substitution at residue 120 (M120I) in exon 4. In addition, a C to T change was introduced to modify the upstream Pstl site. M120I is an autism spectrum disorder-linked mutation found in humans.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • M120I,
  • M120I
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories