Primary Identifier | MGI:6833990 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Helq |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Using CRISPR/Cas9 technology, the first exon of the Helq gene was targeted to induce 8-nt deletion in mouse BVSC ESCs. The targeted ESCs with 8-nt deletion in the two alleles of Helq gene were injected into blastocysts to generate chimeric mice. |