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Allele : Ptpn22<em1Kmow> protein tyrosine phosphatase, non-receptor type 22 (lymphoid); endonuclease-mediated mutation 1, Kerri Mowen
Primary Identifier  MGI:6832841 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Ptpn22
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/cas9 genome editing is used to create an amino acid substitution at position 619 (arginine to tryptophan, CGG to TGG, R619W) in exon 14 and a silent mutation (CTC to CTT) introduced at amino acid position 616 to create a BspE1 restriction site.
  • mutations:
  • Single point mutation
  • synonyms:
  • Ptpn22 619WW,
  • Ptpn22 619WW
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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