| Primary Identifier | MGI:6833875 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change, Reporter | Gene | Mapt |
| Transmission | Germline | Strain of Origin | (C57BL/6 x 129)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeted construct inserted an FRT site, 2 STOP sites, FRT site, 5'PLAP, loxP site, 3'PLAP, loxP site, attB site, neomycin resistance cassette, and attP site. The ALPP (PLAP) coding sequence encodes human placental alkaline phosphatase and its 30 half is inverted and flanked by head-to-head loxP sites, preventing expression in the absence of Cre recombination. The neomycin selection cassette was removed by PhiC31 recombinase. |
