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Allele : Trim24<tm1.2Mcba> tripartite motif-containing 24; targeted mutation 1.2, Michelle Craig Barton

Primary Identifier	MGI:6857763	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Trim24
Transmission	Germline	Strain of Origin	129S6/SvEvTac
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 1 and a loxP site and FRT flanked neo cassette were inserted downstream of exon 1 via homologous recombination. Flp and cre mediated recombination removed the neo cassette and exon 1.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Jiang S, et al. (2015) TRIM24 suppresses development of spontaneous hepatic lipid accumulation and hepatocellular carcinoma in mice. J Hepatol 62(2):371-9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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