| Primary Identifier | MGI:6856706 | Allele Type | Endonuclease-mediated |
| Attribute String | Inserted expressed sequence, Null/knockout | Gene | Dpp4 |
| Strain of Origin | C57BL/6NCrl | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR-targeting inserted exons 2-26 of human DPP4 in-frame into exon 2 of the mouse gene. The insert contains four silent mutations in the coding sequence to prevent CRISPR RNP re-cleavage (see HGVS nomenclature below); it uses the human 3' UTR to terminate transcription and to prevent potential downstream splicing or RNP re-cleavage. |
