Primary Identifier | MGI:6887956 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Ccl28 |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Using CRISPR/Cas9-mediated genome editing, 53 bp in the exon 2 of the Ccl28 gene was deleted causing a reading frame shift and the early translational termination. Quantitative real-time PCR (qRT-PCR) analysis of CCL28 mRNA derived from lung, colon, and salivary glands confirms the absence of mRNA in the homozygous mice. |