Primary Identifier | MGI:6877108 | Allele Type | Targeted |
Attribute String | Modified isoform(s) | Gene | Dmkn |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | By homologous recombination in ES cells, exon 1 of the Dmkn gene was flanked by loxP sites. Frt flanked neo cassette was also inserted in between two loxP sites upstream of exon 1. CAG promoter-driven Cre-mediated loxP recombination deleted exon 1 of the gene which is shared by both beta and gamma isoforms. |