Primary Identifier | MGI:6885945 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | Prickle1 |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated an AGG to CAA change at residues 310-312 resulting in an arginine to glutamine substitution at amino acid 104 (R104Q). This is a mutation seen in progressive myoclonus epilepsy. |