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Allele : Slc31a1<em1Bjme> solute carrier family 31, member 1; endonuclease-mediated mutation 1, Bradley J Merrill

Primary Identifier	MGI:6883631	Allele Type	Endonuclease-mediated
Attribute String	Humanized sequence	Gene	Slc31a1
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR/Cas9 technology generated a cysteine to alanine substitution at amino acid 195 [previously residue187 (C187A)] resulting in a Cys195-oxidation-defective redox-dead Slc31a1 mutant mice. This corresponds to the human C189A.

mutations:
Nucleotide substitutions

synonyms:
mCtr1(C187A),
mCtr1(C187A),
mCtr1<KI>,
mCtr1<KI>

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

2 Publication categories

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