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Allele : Septin12<em1Lych> septin 12; endonuclease-mediated mutation 1, Lingyi Chen

Primary Identifier	MGI:7280674	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Septin12
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR/Cas9 technology deleted nearly the whole open reading frame.

mutations:
Intragenic deletion

synonyms:
Septin12<->,
Septin12<->

earliestPublication:
Chen H, et al. (2022) Homozygous Loss of Septin12, but not its Haploinsufficiency, Leads to Male Infertility and Fertilization Failure. Front Cell Dev Biol 10:850052

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

3 Publication categories

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