| Primary Identifier | MGI:6888035 | Allele Type | Endonuclease-mediated |
| Gene | Ucp1 | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology generated a TGT to GCT change at the redox-regulated residue C254 resulting in a cysteine to alanine substitution at this residue (C254A). This substitution is thought to destabilize the inactive conformation and desensitize UCP1 to activation. |
