Primary Identifier | MGI:7413858 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Amigo2 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The whole coding region was replaced with human placental alkaline phosphatase gene and a neomycin resistance gene under the promoter of the Amigo2 gene. Absence of transcript expression was confirmed by RT-PCR. This is a null allele. RT-qPCR also showed no changes in Amigo1 or Amigo3 mRNA levels suggesting no compensation from the other Amigos. |