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Allele : Cd22<em2Yliu> CD22 antigen; endonuclease-mediated mutation 2, Yang Liu

Primary Identifier	MGI:7413913	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Cd22
Inheritance Mode	Not Specified	Strain of Origin	C57BL/6J
Is Recombinase	false	Is Wild Type	false

description	This allele was generated in the same zygotes as Siglech^em2Yliu.
molecularNote	CRISPR-targeting deleted 17 bp (p.Ser22ArgfsTer23).

mutations:
Intragenic deletion

earliestPublication:
Wang X, et al. (2022) CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder. Cell Metab 34(8):1088-1103.e6

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

2 Publication categories

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