| Primary Identifier | MGI:7280672 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Idh2 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A G-to-A mutation was introduced in exon 4 to change arginine codon 172 (AGG) to lysine (AAG) (p.R172K) and a loxP site flanked neomycin resistance gene cassette was inserted into intron 5. This mutation is associated with myeloid and lymphoid malignancies when found in conjunction with mutations in other genes. |
