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Allele : Trpm7<tm1.2Mfre> transient receptor potential cation channel, subfamily M, member 7; targeted mutation 1.2, Marc Freichel

Primary Identifier  MGI:6890462 Allele Type  Targeted
Attribute String  Null/knockout Gene  Trpm7
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct replaced exon 2 with a tTA and a floxed neomycin resistance cassette driven by a tetracycline response element and CMV promoter. A third loxP site was inserted between exon 2 and 3. Cre-mediated recombination removed the selection cassette, tetracyline response element, and a portion of exon 2.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele