| Primary Identifier | MGI:7414394 | Allele Type | Endonuclease-mediated |
| Attribute String | Modified isoform(s) | Gene | Dnmt3a |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISRP/Cas9 technology deleted exons 3-6, leading to an in-frame deletion of amino acids 22-209 which constitutes 86% of the N terminus. Isoform 1 (Dnmt3a1) thus lacks most of the N terminus but is transcribed normally. Expression of the truncated protein was confirmed in the brain. |
