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Allele : Hlf<em1(cre/ERT2)Smoc> hepatic leukemia factor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center

Primary Identifier	MGI:7262729	Allele Type	Endonuclease-mediated
Attribute String	Conditional ready, Inducible, Recombinase	Gene	Hlf
Strain of Origin	C57BL/6JSmoc	Induced With	tamoxifen
Is Recombinase	true	Is Wild Type	false

molecularNote

CRISPR/Cas9 genome editing technology was used to insert a 2A-Cre and rox flanked ERT2 expression cassette into the exon 4 and 3' UTR of the Hlf gene.

mutations:
Insertion

synonyms:
Hlf<CreER>,
Hlf<CreER>

earliestPublication:
Tang W, et al. (2021) Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate. Front Cell Dev Biol 9:728057

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

1 Driven By

2 Publication categories

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