Primary Identifier | MGI:7280900 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence, Null/knockout | Gene | Prl |
Transmission | Germline | Strain of Origin | 129S/Sv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting vector is designed to replace exon 1 of the gene with the full-length human PRL coding sequence followed by a floxed neomycin cassette. Cre-mediated recombination removed the neo cassette. Immunoblot analysis indicates that mice do not express endogenous prolactin. |