Primary Identifier | MGI:7260342 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | Msh5 |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated a G to T change a position 1456, resulting in an aspartate to tyrosine substitution at residue 486 (p.D486Y) in exon 16 which is equivalent to the human p.D487Y mutation identified in two sisters with primary ovarian insufficiency. |