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Allele : Txnip<tm1.1Jyos> thioredoxin interacting protein; targeted mutation 1.1, Jun Yoshioka

Primary Identifier  MGI:7256567 Allele Type  Targeted
Attribute String  Conditional ready Gene  Txnip
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Two loxP sites were introduced flanking exons 2 to 8 and another set of exons 2-8 containing a T to A change resulting in a cysteine to serine substitution at amino acid 247 (C247S) in exon 5 was incorporated after the second loxP site. In addition, a neomycin selection cassette flanked by self-deletion anchor sites was inserted upstream of the second loxP site and was removed in germ cells.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Txnip<(loxP- exons2-8-loxP)C247S>,
  • Txnip<(loxP- exons2-8-loxP)C247S>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories