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Allele : Foxn1<em1(icre)Smoc> forkhead box N1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center

Primary Identifier  MGI:7263400 Allele Type  Endonuclease-mediated
Attribute String  Recombinase Gene  Foxn1
Strain of Origin  C57BL/6JSmoc Is Recombinase  true
Is Wild Type  false
molecularNote  A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or "winged-helix" transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

2 Publication categories