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Allele : Adar<em2Kawy> adenosine deaminase, RNA-specific; endonuclease-mediated mutation 2, Yukio Kawahara

Primary Identifier  MGI:7264433 Allele Type  Endonuclease-mediated
Attribute String  Hypomorph Gene  Adar
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/cas9 mediated recombination using a single-stranded donor RNA with 2 GCC mutations was used to insert N175A and W197A mutations. This allele was created in embryos from mice homozygous for Ifih1tm1Aki. This mutation reduces RNA editing activity.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Adar1<N175A:W197A>,
  • Adar1<N175A:W197A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories