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Allele : Adam21<em1Liwe> a disintegrin and metallopeptidase domain 21; endonuclease-mediated mutation 1, Wei Li

Primary Identifier  MGI:7294347 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Adam21
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology was used to target the entire open reading frame and create a deletion of 2,324 bp in exon 2. Quantitative RT-PCR analysis confirmed the complete absence of mRNA expression in the testes of homozygous mutant mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Adam21<->,
  • Adam21<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories