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Allele : Pak1<em2Yuwa> p21 (RAC1) activated kinase 1; endonuclease-mediated mutation 2, Yuichi Wakabayashi

Primary Identifier  MGI:7284812 Allele Type  Endonuclease-mediated
Attribute String  No functional change Gene  Pak1
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  Using an sgRNA (targeting GCACTGAAGAGAATTGCATCTGG) and an ssODN templates (CTGCTGGATTACTCGTCCAGATGCAATTCTCTTCAGTGCTAGACAGTTTC) with CRISPR technology, 3' UTR mutation c.*171T>A (minor allele of SNP rs3654376) was introduced to make the 3' UTR in this FVB/N strain similar to that in the MSM/Ms (Mishima Mus musculus molossinus) strain.
  • mutations:
  • Single point mutation
  • synonyms:
  • Pak1-3''UTR-171<A>,
  • Pak1-3''UTR-171<A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories