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Allele : Igs2<em13(Alb-TTR*V50M)Gpt> intergenic site 2; endonuclease-mediated mutation 13, GemPharmatech Co., Ltd

Primary Identifier  MGI:7300626 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence, Inserted expressed sequence, Reporter Gene  Igs2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6JGpt
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR-targeting inserted the mouse promoter driving liver-specific expression of the human gene coding sequence with a mutation that results in the amino acid substitution of valine with methionine at position 50 (V50M). A luciferase reporter gene was also inserted into the locus.
  • mutations:
  • Insertion
  • synonyms:
  • Igs2<em1Cin(Alb- hTTR V50M luciferase)>,
  • Igs2<em1Cin(Alb- hTTR V50M luciferase)>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories