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Allele : Kras<em1Gpt> Kirsten rat sarcoma viral oncogene homolog; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd

Primary Identifier	MGI:7301371	Allele Type	Endonuclease-mediated
Attribute String	Conditional ready	Gene	Kras
Inheritance Mode	Not Specified	Strain of Origin	C57BL/6JGpt
Is Recombinase	false	Is Wild Type	false

molecularNote

CRISPR-targeting inserted a loxP site flanked STOP cassette into intron 1 and a mutation in exon 2 that changes glycine codon 12 to aspartic acid (p.G12D).

mutations:
Single point mutation

synonyms:
Kras<em1Cin(loxP-stop-loxP-G12D)>,
Kras<em1Cin(loxP-stop-loxP-G12D)>

earliestPublication:
Cheng R, et al. (2023) A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers. Cell Res 33(1):30-45

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

4 Publication categories

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