| Primary Identifier | MGI:7284875 | Allele Type | Targeted |
| Attribute String | Humanized sequence, Inserted expressed sequence, Null/knockout | Gene | Itgb2 |
| Transmission | Germline | Strain of Origin | C57BL/6N |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting cassette contains a loxP site, followed by an FRT-flanked neomycin selection cassette, the human ITGB2 isoform 1 cDNA, polyA sequence and a second loxP site inserted into exon 2 of the gene. The insertion of this cassette results in disruption of the endogenous gene and no mouse Itgb2 is expressed. Flp-mediated recombination removed the neo cassette. |
