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Allele : Acss2<em22Gpt> acyl-CoA synthetase short-chain family member 2; endonuclease-mediated mutation 22, GemPharmatech Co., Ltd
Primary Identifier  MGI:7309378 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Acss2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6JGpt
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR-targeting introduced a coding region modification (del4454). Western blotting and immunofluorescence analyses of kidney tissues confirmed the absence of protein expression in homozygous mutant mice. LPS treatment failed to increase the protein levels of ACSS2 in mutant kidneys, unlike in wild-type controls.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • ACSS2 KO,
  • Acss2<em22Cd4454>,
  • ACSS2 KO,
  • ACSS2<->,
  • ACSS2<->,
  • Acss2<em22Cd4454>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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