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Allele : Sox30<em1Laye> SRY (sex determining region Y)-box 30; endonuclease-mediated mutation 1, Lan Ye

Primary Identifier  MGI:7310078 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Sox30
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a 47-bp deletion in exon 2 within the HMG Box domain. This deletion produces a premature termination codon. RT-PCR and Western blot analysis confirmed the absence of full-length transcript and protein, respectively, in testis lysates from adult homozygous mutant mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Sox30<->,
  • Sox30<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories