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Allele : Cd3e<em2(CD3E)Smoc> CD3 antigen, epsilon polypeptide; endonuclease-mediated mutation 2, Shanghai Model Organisms Center

Primary Identifier	MGI:7288821	Allele Type	Endonuclease-mediated
Attribute String	Humanized sequence, Inserted expressed sequence	Gene	Cd3e
Inheritance Mode	Not Specified	Strain of Origin	C57BL/6JSmoc
Is Recombinase	false	Is Wild Type	false

molecularNote

This PD-1 and CD3e double knockin strain is established by crossing PD-1-HU and CD3e-HU mice together. These double double knockin mouse models can be useful for evaluating the efficacy of potential immunotherapy drug combinations.

mutations:
Insertion,
Intragenic deletion

synonyms:
Cd3e<em1(hCD3E)Smoc>,
Cd3e<em1(hCD3E)Smoc>

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

3 Publication categories

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