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Allele : Gt(ROSA)26Sor<em52(CAG-KRAB,-cas9*,-EGFP)Smoc> gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 52, Shanghai Model Organisms Center
Primary Identifier  MGI:7290061 Allele Type  Endonuclease-mediated
Attribute String  Endonuclease, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Inheritance Mode  Not Specified Strain of Origin  C57BL/6JSmoc
Is Recombinase  false Is Wild Type  false
molecularNote  These mice harbor a CAG-LSL-3xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted.
  • mutations:
  • Insertion
  • synonyms:
  • Gt(ROSA)26Sor<em1(CAG-LSL-KRAB-dCas9-IRES-EGFP)Smoc>,
  • Gt(ROSA)26Sor<em1(CAG-LSL-KRAB-dCas9-IRES-EGFP)Smoc>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

2 Publication categories





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