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Allele : Igs2<em3(CAG-EYFP)Smoc> intergenic site 2; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Primary Identifier  MGI:7290388 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready, Reporter Gene  Igs2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6JSmoc
Is Recombinase  false Is Wild Type  false
molecularNote  A CAG-ROX-STOP-ROX-EYFP-V5tag-polyA conditional expression cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) . This strain of mice can be used to mate with mice expressing the Dre recombinase. After exposure to Dre recombinase, expression of ellow fluorescent protein and V5 tag is observed for cell tracking.
  • mutations:
  • Insertion
  • synonyms:
  • Igs2<em1(CAG-RSR-EYFP)Smoc>,
  • Igs2<em1(CAG-RSR-EYFP)Smoc>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

0 Driven By

3 Publication categories





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