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Allele : Cdkn1b<tm1.1 Hjak> cyclin dependent kinase inhibitor 1B; targeted mutation 1.1, Heidelinde Jakel

Primary Identifier  MGI:7330388 Allele Type  Targeted
Attribute String  Not Specified Gene  Cdkn1b
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was modified by insertion of a loxP-flanked neomycin resistance cassette in intron 2 and an A-to-T mutation in exon 1, changing tyrosine codon 88 (TAC) to phenylalanine (TTC) in the CDK-binding domain coding region (c.263A>T, p.Y88F). The Neomycin cassette was excised by breeding with Sox2-Cre mice.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • p27-Y88F,
  • p27-Y88F
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories