| Primary Identifier | MGI:7330388 | Allele Type | Targeted |
| Attribute String | Not Specified | Gene | Cdkn1b |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was modified by insertion of a loxP-flanked neomycin resistance cassette in intron 2 and an A-to-T mutation in exon 1, changing tyrosine codon 88 (TAC) to phenylalanine (TTC) in the CDK-binding domain coding region (c.263A>T, p.Y88F). The Neomycin cassette was excised by breeding with Sox2-Cre mice. |