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Allele : Rr249<em3Ebres> regulatory region 249; endonuclease-mediated mutation 3, Emery H Bresnick

Primary Identifier  MGI:7330394 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr249
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  The intronic Gata2 enhancer was targeted with an sgRNA (targeting TCTCCTGCCGGAGTTTCCTATCCGG) using CRISPR/Cas9 technology, resulting in a 47 bp deletion (CTATCCGGACATCTGCAGCCGGTAGATAAGGAAACTTCGTGTATCTG) that deletes the E-box and Gata-binding sequences.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Gata2 +9.5<->,
  • Gata2 +9.5<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories