| Help | About | Contact Us

Allele : Wwc2<tm1.1Fxyu> WW, C2 and coiled-coil domain containing 2; targeted mutation 1.1, Fa-Xing Yu

Primary Identifier	MGI:7314960	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Wwc2
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

The targeting construct introduced a loxP site upstream of exon 2 and an Rox-flanked neomycin resistance cassette with a 3 prime loxP site. Dre-mediated recombination removed the selection cassette.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Wwc2<F>,
Wwc2<F>

earliestPublication:
Qi S, et al. (2022) WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy. Mol Cell 82(10):1850-1864.e7

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76795032

MouseMine