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Allele : Rr253<em2Kmm> regulatory region 253; endonuclease-mediated mutation 2, Kenneth M Murphy

Primary Identifier  MGI:7331607 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr253
Strain of Origin  STOCK Zeb2<tm2.1Yhi>/2YhiRbrc Is Recombinase  false
Is Wild Type  false
molecularNote  The Zeb2 enhancer, containing four E-boxes and located ~165 kb upstream, was targeted with sgRNAs (targeting GAGAGATCATCAAATG and GATAACGTTCTTGAAGCATA) using CRISPR/Cas9 technology, resulting in a 368 bp deletion. The allele was created in zygotes containing the Zeb2tm2.1Yhi allele.
  • mutations:
  • Intergenic deletion
  • synonyms:
  • Zeb2<delta-165>,
  • Zeb2<delta-165>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories